Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.50 |
| ▸ | CNR1 | P21554 | 11/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.50 |
| ▸ | TRPV2 | Q9Y5S1 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24212712 | 0.83 | CNR2 (0.43) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL20825151 | 0.80 | CNR2 (0.75) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL31546065 | 0.80 | CNR2 (0.75) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL31545705 | 0.78 | CNR2 (0.71) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL24335024 | 0.77 | CNR2 (0.77) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL30641143 | 0.70 | PDK2 (0.45) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL24714645 | 0.70 | CNR2 (0.78) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL29814936 | 0.70 | CNR2 (0.78) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL13214141 | 0.69 | CNR2 (0.81) | CNR2CNR1TRPA1TRPV1TRPV3 | |
| SCHEMBL29814933 | 0.69 | CNR2 (0.81) | CNR2CNR1TRPA1TRPV1TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017482-A1 | Synthetic Antibacterial Compounds and Uses Thereof | UNIV MCMASTER (CA) | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017482-A1 | Synthetic Antibacterial Compounds and Uses Thereof | SPOUT1, NRDC, MRPL21 | CNR2 4460/4885CNR1 4339/4885TRPA1 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.