Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 0.73 |
| ▸ | RAB9A | P51151 | 10/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.73 |
| ▸ | TP53 | P04637 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 3/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.69 |
| ▸ | RELA | Q04206 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21485722 | 0.84 | NPC1 (0.77) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL21480513 | 0.82 | SMN1; SMN2 (0.73) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL13525245 | 0.82 | NPC1 (0.80) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7291752 | 0.81 | NR1H4 (1.00) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6697420 | 0.81 | NR1H4 (1.00) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL11555058 | 0.79 | NR1H4 (0.64) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28803404 | 0.78 | S1PR1 (0.78) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL26095666 | 0.78 | MAPT (0.72) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL24212404 | 0.78 | NR1H4 (1.00) | NR1H4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL2771674 | 0.77 | S1PR1 (1.00) | NR1H4NPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220016136-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS | VIKING THERAPEUTICS, INC. | 2022-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220016136-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS | FABP1, SLC10A1, TSHR | NR1H4 11/4885NPC1 201/4885RAB9A 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.