Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzothiazolylcysteine SCHEMBL30368578 | 0.78 | POLB (0.61) | ALDH1A1HPGDPOLBSMN1; SMN2MAPK1 | |
| Benzothiazolylcysteine SCHEMBL8963327 | 0.78 | POLB (0.61) | ALDH1A1HPGDPOLBSMN1; SMN2MAPK1 | |
| Benzothiazolylcysteine SCHEMBL8963324 | 0.78 | POLB (0.61) | ALDH1A1HPGDPOLBSMN1; SMN2MAPK1 | |
| SCHEMBL24214286 | 0.75 | PSMB8 (0.49) | ALDH1A1HPGDSMN1; SMN2HSD17B10TSHR | |
| SCHEMBL11105656 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL476051 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL476053 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL29380724 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| Benzene SCHEMBL28251054 | 0.73 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| Bromide SCHEMBL7413848 | 0.72 | SMN1; SMN2 (0.54) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013564-A1 | PHOTOREDOX PROTEIN MODIFICATION | THE ROSALIND FRANKLIN INSTITUTE (GB) | 2022-01-20 | — | — | WO | disclosed |