Benzothiazolylcysteine

Benzothiazolylcysteine

SCHEMBL8963327

N[C@@H](CSc1nc2ccccc2s1)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.61
APEX1 P27695 2/20 0.61
RECQL P46063 1/20 0.61
ALDH1A1 P00352 6/20 0.60
HPGD P15428 4/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
MAPK1 P28482 2/20 0.60
TSHR P16473 1/20 0.60
HSD17B10 Q99714 1/20 0.60
MAPT P10636 3/20 0.58
CYP1A2 P05177 3/20 0.56
CYP2D6 P10635 3/20 0.56
CYP3A4 P08684 2/20 0.56
CYP2C19 P33261 2/20 0.56
HIF1A Q16665 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzothiazolylcysteine SCHEMBL8963324 1.00 POLB (0.61) POLBAPEX1RECQLALDH1A1HPGD
Benzothiazolylcysteine SCHEMBL30368578 1.00 POLB (0.61) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL10821618 0.83 APEX1 (0.62) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL8972076 0.81 ALDH1A1 (0.61) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL9811145 0.81 MAPT (0.59) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL9811169 0.80 MAPT (0.58) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL10358412 0.80 ALDH1A1 (0.60) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL10890573 0.80 ALDH1A1 (0.60) POLBAPEX1RECQLALDH1A1HPGD
SCHEMBL8971875 0.80 ALDH1A1 (0.60) POLBAPEX1RECQLALDH1A1HPGD
Ammonia Solution, Strong SCHEMBL10895431 0.80 ALDH1A1 (0.60) POLBAPEX1RECQLALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 US claimed
US-12429483-B2 System and method for determining onset and disease progression RESPIRATION SCAN LTD (IL) 2025-09-30 US disclosed
EP-4164481-B1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2024-10-16 EP disclosed
US-20230337934-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2023-10-26 US disclosed
EP-4164481-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH Nanose Medical Ltd (IL) 2023-04-19 EP disclosed
US-20220317122-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION RESPIRATION SCAN LTD. (IL) 2022-10-06 US disclosed
EP-4013302-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION Respiration Scan Ltd (IL) 2022-06-22 EP disclosed
WO-2021250674-A1 A DEVICE FOR MEASURING VOLATILE MARKERS IN BREATH NANOSE MEDICAL LTD (IL) 2021-12-16 WO disclosed
WO-2021028928-A1 SYSTEM AND METHOD FOR DETERMINING ONSET AND DISEASE PROGRESSION RESPIRATION SCAN LTD (IL) 2021-02-18 WO disclosed
US-5578470-A USING CYSTEINE NEDERLANDSE ORGANISATIE VOOR TOEGEPAST (NL) 1996-11-26 US disclosed
US-5495044-A Inhibitors of kynureninase UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-02-27 US disclosed
US-5442104-A Neurological disorders UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1995-08-15 US disclosed
WO-1995011878-A1 INHIBITORS OF KYNURENINASE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1995-05-04 WO disclosed
EP-0581907-A4 1994-04-06 EP disclosed
EP-0581907-A1 INHIBITORS OF KYNURENINASE THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1994-02-09 EP disclosed
EP-0277688-B1 Method for preparing thiol compounds TNO (NL) 1993-10-27 EP disclosed
US-5254725-A Inhibitors of kynureninase UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-10-19 US disclosed
US-5182194-A Biosynthesis, reaction of pulegone and cysteine NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPE LIJK ONDERZOEKTNO (NL) 1993-01-26 US disclosed
WO-1992018003-A1 INHIBITORS OF KYNURENINASE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1992-10-29 WO disclosed
EP-0277688-A2 Method for preparing thiol compounds NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1988-08-10 EP disclosed