Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215470 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL30411412 | 0.86 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL24215713 | 0.85 | ALKBH2 (0.40) | SCN10AHPGDS | |
| SCHEMBL24215327 | 0.79 | PTPN1 (0.38) | ABL1SCN10AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30412177 | 0.79 | PTPN1 (0.38) | ABL1SCN10AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL23622940 | 0.79 | SCN10A (0.39) | ABL1SCN10AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24215714 | 0.79 | SCN10A (0.37) | ABL1SCN10AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30412622 | 0.78 | SCN10A (0.36) | ABL1SCN10AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL25025740 | 0.77 | SCN10A (0.37) | ABL1SCN10AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24215439 | 0.76 | HDAC6 (0.39) | SCN10AALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |