Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23622940 | 0.84 | SCN10A (0.39) | SCN10APIK3CAMTORMAPTSMN1; SMN2 | |
| SCHEMBL23622921 | 0.83 | SMN1; SMN2 (0.48) | SCN10AMAPTSMN1; SMN2ALDH1A1DRD2 | |
| SCHEMBL1816828 | 0.77 | HRH4 (0.50) | MAPTGAAGFERSMN1; SMN2ALDH1A1 | |
| SCHEMBL14782147 | 0.77 | ALDH1A1 (0.47) | TRPV1MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL14784205 | 0.77 | ALDH1A1 (0.43) | TRPV1MAPTGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL23623107 | 0.77 | PIK3CA (0.48) | PIK3CAMTORMAPTGAARAD52 | |
| Hydrochloric Acid SCHEMBL4752368 | 0.76 | HRH4 (0.49) | MAPTGAARAD52GFERSMN1; SMN2 | |
| SCHEMBL30336490 | 0.76 | TRPV1 (0.42) | TRPV1SCN10APIK3CAMTORMAPT | |
| SCHEMBL25199994 | 0.76 | TRPV1 (0.42) | TRPV1SCN10APIK3CAMTORMAPT | |
| SCHEMBL23623623 | 0.76 | JAK2 (0.40) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |