⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30413030 | 0.85 | BACE2 (0.33) | — | |
| SCHEMBL24215427 | 0.85 | BACE2 (0.33) | — | |
| SCHEMBL24214080 | 0.76 | HCAR2 (0.36) | — | |
| SCHEMBL24215525 | 0.76 | HDAC6 (0.33) | — | |
| SCHEMBL24214081 | 0.73 | MAPK1 (0.37) | — | |
| SCHEMBL27020185 | 0.73 | CYP3A4 (0.32) | — | |
| SCHEMBL20332332 | 0.71 | CYP11B1 (0.33) | — | |
| SCHEMBL38657142 | 0.70 | — | — | |
| SCHEMBL24215529 | 0.69 | RORC (0.33) | — | |
| SCHEMBL23623071 | 0.68 | PIK3CA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| EP-4182028-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |
| WO-2022015957-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2022-01-20 | — | — | WO | disclosed |