Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.94 |
| ▸ | PPARG | P37231 | 7/20 | 0.94 |
| ▸ | PPARD | Q03181 | 7/20 | 0.94 |
| ▸ | PPARA | Q07869 | 7/20 | 0.94 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.94 |
| ▸ | FABP4 | P15090 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | TLR2 | O60603 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.94 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | PDE4A | P27815 | 1/20 | 0.94 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL7062493 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL24895 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL3972949 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Undecanoate SCHEMBL5527083 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL5144260 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL25434319 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL55414 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL16585379 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL11319185 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL14763615 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12202973-B1 | Class a fire-retardant polyisocyanurate foam boards and process for making | DDP SPECIALTY ELECTRONIC MATERIALS US, LLC (US) | 2025-01-21 | — | — | US | disclosed |
| US-20240130957-A1 | EXTRACTS OF ISOCHRYSIS SPECIES/TISOCHRYSIS SPECIES | SYMRISE AG (DE) | 2024-04-25 | — | — | US | disclosed |
| EP-2766406-B1 | HYBRID POLYESTER-POLYETHER POLYOLS FOR IMPROVED DEMOLD EXPANSION IN POLYURETHANE RIGID FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-11-25 | — | — | EP | disclosed |
| CN-111514040-A | Powder composition dispersed by fine particle process and method for producing the same | 科丝美诗株式会社 | 2020-08-11 | — | — | CN | disclosed |
| EP-2285859-B1 | 1,3- OR 1,4-BIS(AMINOMETHYL)CYCLOHEXANE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-03-18 | — | — | EP | disclosed |
| EP-2115027-B1 | CIS AND/OR TRANS-ORTHO-CYCLOHEXANEDIAMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-10-03 | — | — | EP | disclosed |
| EP-2115026-B1 | AMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-02 | — | — | EP | disclosed |
| CN-107352877-A | A kind of azulejo watt and its production technology | 寿县维东建材商贸有限公司 | 2017-11-17 | — | — | CN | disclosed |
| US-9758614-B2 | Polyester polyol and polyol blends and rigid polyurethane foam manufacturing | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-09-12 | — | — | US | disclosed |
| CN-104144672-B | Waterborne liquid make-up composition including alkylcellulose, nonvolatile oil and at least one surfactant | 欧莱雅 | 2016-11-16 | — | — | CN | disclosed |
| WO-2009152044-A1 | 1,3- OR 1,4-BIS(AMINOMETHYL)CYCLOHEXANE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009152045-A1 | METHYLENE BIS(CYCLOHEXYLAMINE)-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFORM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-12-17 | — | — | WO | disclosed |
| EP-2115027-A1 | CIS AND/OR TRANS-ORTHO-CYCLOHEXANEDIAMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | Dow Global Technologies Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| EP-2115026-A1 | AMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | Dow Global Technologies Inc. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2009091705-A2 | THERMALLY INSULATING ISOCYANATE-BASED FOAMS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2009-07-23 | — | — | WO | disclosed |
| WO-2008094963-A1 | CIS AND/OR TRANS-ORTHO-CYCLOHEXANEDIAMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008094238-A1 | ORTHO-CYCLOHEXANEDIAMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008094239-A1 | AMINE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2008-08-07 | — | — | WO | disclosed |
| CN-1209366-C | Preparation of fatty acid esters of carbohydrates | JO IN HO (KR) | 2005-07-06 | — | — | CN | disclosed |
| US-5302482-A | Liquid electrophotographic toner | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-04-12 | — | — | US | disclosed |