Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25350208 | 0.92 | HDAC6 (0.39) | HDAC6HDAC1 | |
| SCHEMBL30408954 | 0.92 | HDAC6 (0.39) | HDAC6HDAC1 | |
| SCHEMBL24216833 | 0.89 | HDAC1 (0.41) | HDAC6HDAC1 | |
| SCHEMBL25351039 | 0.88 | HDAC6 (0.40) | HDAC6HDAC1 | |
| SCHEMBL30460273 | 0.88 | HDAC6 (0.40) | HDAC6HDAC1 | |
| SCHEMBL24216896 | 0.86 | HDAC1 (0.41) | HDAC6HDAC1 | |
| SCHEMBL24216715 | 0.86 | HDAC6 (0.53) | HDAC6HDAC1 | |
| SCHEMBL25350746 | 0.85 | HDAC1 (0.42) | HDAC6HDAC1 | |
| SCHEMBL25351908 | 0.84 | HDAC1 (0.40) | HDAC6HDAC1 | |
| SCHEMBL30409806 | 0.81 | MET (0.39) | HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013728-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2022-01-20 | — | — | WO | disclosed |