Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 7/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015345 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL2422006 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL3514273 | 1.00 | SLC7A5 (0.62) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| Hydrochloric Acid SCHEMBL8663720 | 0.98 | SLC7A5 (0.60) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| Hydrochloric Acid SCHEMBL6954433 | 0.98 | SLC7A5 (0.60) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL7460997 | 0.84 | SLC7A5 (0.60) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL2420111 | 0.82 | SLC7A5 (0.58) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL6138683 | 0.82 | SLC7A5 (0.58) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL199134 | 0.82 | SLC7A5 (0.58) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 | |
| SCHEMBL8015716 | 0.82 | SLC7A5 (0.58) | SLC7A5SLC1A2SLC1A1SLC1A3GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114599389-A | Variant FC domains and uses thereof | 奇达拉治疗公司 | 2022-06-07 | — | — | CN | disclosed |
| US-8765910-B2 | Method for amidating polypeptides with basic amino acid C-terminals by means of specific endoproteases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-07-01 | — | — | US | disclosed |
| EP-1931705-B1 | METHOD FOR AMIDATING POLYPEPTIDES WITH BASIC AMINOACID C- TERMINALS BY MEANS OF SPECIFIC ENDOPROTEASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-07 | — | — | EP | disclosed |
| US-20100311112-A1 | METHOD FOR AMIDATING POLYPEPTIDES WITH BASIC AMINO ACID C-TERMINALS BY MEANS OF SPECIFIC ENDOPROTEASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-12-09 | — | — | US | disclosed |
| CN-101268097-A | Method for amidating polypeptides with a basic amino acid C-terminus by means of specific endoproteases | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-09-17 | — | — | CN | disclosed |
| EP-1931705-A2 | METHOD FOR AMIDATING POLYPEPTIDES WITH BASIC AMINOACID C- TERMINALS BY MEANS OF SPECIFIC ENDOPROTEASES | Sanofi-Aventis Deutschland GmbH (DE) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007036299-A2 | METHOD FOR AMIDATING POLYPEPTIDES WITH BASIC AMINOACID C- TERMINALS BY MEANS OF SPECIFIC ENDOPROTEASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-04-05 | — | — | WO | disclosed |
| EP-0649303-B1 | SUBSTITUTED ARGININES AND SUBSTITUTED HOMOARGININES AND USE THEREOF | CORNELL RES FOUNDATION INC (US) | 1998-11-25 | — | — | EP | disclosed |
| US-5663364-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-5476871-A | Method for the treatment of hypotension induced by a cytokine or bacterial endotoxin using s-alkyl- isothioureido-amino acids | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-12-19 | — | — | US | disclosed |
| US-5464858-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| US-5453441-A | Enzyme inhibitors and hypertensive agents | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| EP-0649303-A4 | SUBSTITUTED ARGININES AND SUBSTITUTED HOMOARGININES AND USE THEREOF. | CORNELL RES FOUNDATION INC (US) | 1995-07-05 | — | — | EP | disclosed |
| US-5424447-A | Heme binding compounds and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1995013804-A1 | S-ALKYL-ISOTHIOUREIDO-AMINO ACIDS AND USE THEREOF | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1995-05-26 | — | — | WO | disclosed |
| EP-0649303-A1 | SUBSTITUTED ARGININES AND SUBSTITUTED HOMOARGININES AND USE THEREOF | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| US-5364881-A | S-alkyl-isothioureido-amino acids and use thereof | THE MEDICAL COLLEGE OF WISCONSIN RESEARCH FOUNDATION, INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5281627-A | Guanidine substituted arginines | CORNELL RESEARCH FOUNDATION, INC. (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1993024126-A1 | SUBSTITUTED ARGININES AND SUBSTITUTED HOMOARGININES AND USE THEREOF | CORNELL RESEARCH FOUNDATION, INC. (US) | 1993-12-09 | — | — | WO | disclosed |