Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 3/20 | 0.44 |
| ▸ | SUV39H2 | Q9H5I1 | 4/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339061 | 0.86 | PAICS (0.60) | PAICSSUV39H2PDE3BPDE3AP2RY12 | |
| SCHEMBL20352114 | 0.81 | PAICS (0.56) | PAICSPDE3BPDE3AP2RY12MAPT | |
| SCHEMBL20339071 | 0.76 | PAICS (0.59) | PAICSSUV39H2 | |
| SCHEMBL20339037 | 0.75 | PAICS (0.48) | PAICSSUV39H2PDE3BPDE3AP2RY12 | |
| SCHEMBL24220497 | 0.72 | PAICS (0.43) | PAICSSUV39H2PDE3BPDE3AP2RY12 | |
| SCHEMBL20352132 | 0.70 | PAICS (0.59) | PAICSMAPTMAPK1HTT | |
| SCHEMBL24220517 | 0.70 | MAPT (0.48) | PDE3BPDE3AMAPTMAPK1HTT | |
| SCHEMBL20352021 | 0.70 | PAICS (0.48) | PAICSPDE3BPDE3AP2RY12MAPT | |
| SCHEMBL20352111 | 0.69 | SMN1; SMN2 (0.47) | PAICSMAPTHTTSMN1; SMN2 | |
| SCHEMBL24220501 | 0.69 | GAA (0.54) | MAPTMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |