Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049784 | 0.80 | GFER (0.55) | GAALMNAMAPTKDM4ETSHR | |
| SCHEMBL314250 | 0.78 | HTR1A (0.54) | GAALMNAMAPTKDM4ETSHR | |
| SCHEMBL3048329 | 0.76 | MAPT (0.73) | LMNAMAPTL3MBTL1HTTMAPK1 | |
| SCHEMBL5232354 | 0.74 | FAAH (0.61) | GAALMNAMAPTKDM4EL3MBTL1 | |
| SCHEMBL10401849 | 0.74 | CHRM4 (0.54) | LMNAMAPTKDM4EHTTHRH3 | |
| SCHEMBL5539971 | 0.74 | MAPT (0.76) | GAALMNAMAPTKDM4ETSHR | |
| SCHEMBL5539965 | 0.74 | MAPT (0.59) | GAALMNAMAPTKDM4ETSHR | |
| SCHEMBL3313011 | 0.73 | MAPT (0.58) | GAALMNAMAPTKDM4EL3MBTL1 | |
| SCHEMBL5541814 | 0.73 | MAPT (0.74) | GAALMNAMAPTKDM4ETSHR | |
| SCHEMBL5541807 | 0.73 | MAPT (0.58) | GAALMNAMAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |