SCHEMBL24222020

SCHEMBL24222020

CCOC(=O)[C@@H](NC(=O)c1nn(CCCCF)c2ccccc12)C(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 15/20 0.65
CNR2 P34972 13/20 0.65
HTR3A P46098 2/20 0.45
KDM4E B2RXH2 1/20 0.44
HTR4 Q13639 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809369 0.99 CNR1 (0.65) CNR1CNR2HTR3AKDM4E
SCHEMBL30258887 0.92 CNR1 (0.65) CNR1CNR2HTR3AKDM4E
SCHEMBL31052992 0.92 CNR1 (0.65) CNR1CNR2HTR3AKDM4E
SCHEMBL24221986 0.92 CNR1 (0.73) CNR1CNR2HTR3AKDM4E
SCHEMBL30641079 0.91 CNR1 (0.67) CNR1CNR2HTR3A
SCHEMBL29993181 0.91 CNR1 (0.67) CNR1CNR2HTR3A
SCHEMBL31462484 0.88 CNR1 (0.67) CNR1CNR2HTR3AKDM4EHTR4
SCHEMBL30641078 0.86 CNR1 (0.77) CNR1CNR2HTR3AKDM4E
SCHEMBL25366701 0.86 CNR1 (0.80) CNR1CNR2HTR3AKDM4E
SCHEMBL30353000 0.86 CNR1 (0.80) CNR1CNR2HTR3AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220026380-A1 NUCLEAR MAGNETIC RESONANCE IMPLEMENTED SYNTHETIC INDOLE AND INDAZOLE CANNABINOID DETECTION, IDENTIFICATION, AND QUANTIFICATION HOFSTRA UNIVERSITY (US) 2022-01-27 US disclosed