SCHEMBL29993181

SCHEMBL29993181

COC(=O)C(NC(=O)c1nn(CCCCCF)c2ccccc12)C(C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 18/20 0.67
CNR2 P34972 17/20 0.66
HTR3A P46098 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30641079 1.00 CNR1 (0.67) CNR1CNR2HTR3A
SCHEMBL30258887 0.99 CNR1 (0.65) CNR1CNR2HTR3A
SCHEMBL31052992 0.99 CNR1 (0.65) CNR1CNR2HTR3A
SCHEMBL29809369 0.92 CNR1 (0.65) CNR1CNR2HTR3A
SCHEMBL24222020 0.91 CNR1 (0.65) CNR1CNR2HTR3A
SCHEMBL30353000 0.89 CNR1 (0.80) CNR1CNR2HTR3A
SCHEMBL25366701 0.89 CNR1 (0.80) CNR1CNR2HTR3A
SCHEMBL31462484 0.89 CNR1 (0.67) CNR1CNR2HTR3A
SCHEMBL4049645 0.87 CNR1 (0.62) CNR1CNR2HTR3A
SCHEMBL29871232 0.87 CNR1 (0.80) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
CN-115963258-B Detection method and detection kit for synthetic cannabinoid 上海八通生物科技股份有限公司 2025-01-17 CN claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
CN-115963258-A Detection method and detection kit for synthetic cannabinoid 上海八通生物科技股份有限公司 2023-04-14 CN claimed
CN-113267589-B Analysis method of 16 synthetic cannabinoids and metabolites thereof in hair 司法鉴定科学研究院 2022-11-04 CN claimed
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES INC (US) 2025-11-27 US disclosed
EP-4646477-A2 METHODS AND COMPOSITIONS FOR DISPLAYING PEPTIDE LIBRARIES Board of Regents, The University of Texas System (US) 2025-11-12 EP disclosed
EP-4639145-A1 SYNTHETIC CANNABINOID DETECTION The University of Bath (GB) 2025-10-29 EP disclosed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP disclosed
US-20250241933-A1 METHODS OF TREATING SLEEP APNEA WITH A COMBINATION OF A CANNABINOID AND A CARBONIC ANHYDRASE INHIBITOR APNIMED, INC. (DELAWARE) 2025-07-31 US disclosed
US-20250216329-A1 DRUG DETECTION THE UNIVERSITY OF BATH (GB) 2025-07-03 US disclosed
WO-2025137725-A2 A METHOD OF CULTIVATING, PREPARING, AND USING A MATRIX-BLANK BIOMASS PAULI CHRISTOPHER STEPHEN (US) 2025-06-26 WO disclosed
WO-2023102541-A1 METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-06-08 WO disclosed
CN-115963258-A Detection method and detection kit for synthetic cannabinoid 上海八通生物科技股份有限公司 2023-04-14 CN disclosed
US-11612581-B2 Cannabis and derivatives thereof for the treatment of pain and inflammation related with dental pulp and bone regeneration related to dental jaw bone defects CANNIBITE BVBA 2023-03-28 US disclosed
CN-115728280-A On-site detection method of synthetic cannabinoid JWH-018 中国科学院新疆理化技术研究所 2023-03-03 CN disclosed
US-20220406587-A1 MASS SPECTROMETRY METHODS AND RELATED MATERIALS THE TRUSTEES OF INDIANA UNIVERSITY 2022-12-22 US disclosed
CN-113267589-B Analysis method of 16 synthetic cannabinoids and metabolites thereof in hair 司法鉴定科学研究院 2022-11-04 CN disclosed
WO-2022221613-A1 COMBINATION OF A NOREPINEPHRINE REUPTAKE INHIBITOR AND A CANNABINOID FOR USE IN TREATING SLEEP APNEA APNIMED, INC. (DELAWARE) (US) 2022-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250360137-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES PDE9A, PDE3A, PDE2A CNR1 221/4885CNR2 204/4885HTR3A 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.