SCHEMBL2422356

SCHEMBL2422356

N#CC(c1ccccc1)(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 9/20 0.56
ESR1 P03372 8/20 0.56
CYP3A4 P08684 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CA12 O43570 2/20 0.43
CA2 P00918 2/20 0.43
CA3 P07451 2/20 0.43
CA9 Q16790 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA1 P00915 1/20 0.43
GLA P06280 1/20 0.43
CA4 P22748 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MMP3 P08254 1/20 0.42
BCL2L1 Q07817 1/20 0.42
KIF11 P52732 3/20 0.42
LMNA P02545 1/20 0.41
TYR P14679 1/20 0.41
AR P10275 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10398742 0.91 ESR1 (0.54) ESR2ESR1CYP3A4ALDH1A1CA12
SCHEMBL1444134 0.85 ATM (0.45) CYP3A4ALDH1A1TSHR
SCHEMBL9412369 0.85 ESR1 (0.51) ESR2ESR1CYP3A4ALDH1A1KIF11
SCHEMBL26629625 0.83 ESR2 (0.52) ESR2ESR1CYP3A4ALDH1A1CA12
SCHEMBL1552420 0.80 ESR1 (0.54) ESR2ESR1CYP3A4ALDH1A1CA12
SCHEMBL17817924 0.77 TSHR (0.43) CYP3A4ALDH1A1TDP1KIF11TSHR
SCHEMBL1443801 0.77 KCNN4 (0.47) CYP3A4ALDH1A1KIF11LMNAHPGD
SCHEMBL2392348 0.77 KCNN4 (0.47) CYP3A4ALDH1A1KIF11LMNAHPGD
SCHEMBL2390778 0.77 KIF11 (0.44) KIF11TSHRSLC6A2SLC6A4SLC6A3
Phosphonic Acid SCHEMBL27364417 0.77 ATM (0.37) CYP3A4ALDH1A1TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1805130-B1 METHOD FOR THE PREPARATION OF ALIPHATIC CHLOROFORMATES SABIC INNOVATIVE PLASTICS IP (NL) 2015-01-28 EP disclosed
EP-1945696-B1 METHOD OF IMPROVING ABRASION RESISTANCE OF PLASTIC ARTICLE USING FUNCTIONALIZED POLYMERS AND ARTICLE PRODUCED THEREBY SABIC INNOVATIVE PLASTICS IP (NL) 2013-07-31 EP disclosed
EP-1971631-B1 THERMALLY STABLE POLYCARBONATES, THERMOPLASTIC COMPOSITIONS THEREOF, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2011-09-21 EP disclosed
US-7855241-B2 Method of improving abrasion resistance of plastic article using nanoparticles and article produced thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-12-21 US disclosed
EP-1969058-B1 POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM, WITH MATTE SURFACES AND HIGH LIGHT TRANSMISSIONS SABIC INNOVATIVE PLASTICS IP (NL) 2010-08-25 EP disclosed
US-7728059-B2 Polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-06-01 US disclosed
US-7696371-B2 Method for the prepration of aliphatic chloroformates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-04-13 US disclosed
US-7632881-B2 Comprises an effective amount of a polycarbonate, an anti-dripping agent, an aromatic sulfone sulfonate, an aromatic sulfonate, a synergistic combination of an elastomer-modified graft copolymer and a polysiloxane-polycarbonate copolymer; improved fire-retardance; electronics SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-12-15 US disclosed
EP-1984473-B1 HALOGEN-FREE POLYCARBONATE COMPOSITIONS AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2009-11-25 EP disclosed
US-6162876-A Cyanate ester based thermoset compositions GENERAL ELECTRIC COMPANY (US) 2000-12-19 US disclosed
US-6051662-A POLYPHENYLENE ETHER RESIN COMPONENT HAS A MOLECULAR WEIGHT OF LESS THAN ABOUT 3000 NUMBER AVERAGE IN CONTRAST TO HIGHER POLYPHENYLENE ETHERS EMPLOYED IN OTHER POLYPHENYLENE ETHER-THERMOSETTING RESIN FOR USE IN PRINTED CIRCUIT BOARD GENERAL ELECTRIC CO. (US) 2000-04-18 US disclosed
EP-0962495-A1 A curable polyphenylene ether-thermosetting resin composition GENERAL ELECTRIC COMPANY (US) 1999-12-08 EP disclosed
EP-0945477-A1 Cyanate ester based thermoset compositions GENERAL ELECTRIC COMPANY (US) 1999-09-29 EP disclosed
EP-0921158-A2 Poly(phenylene ether) thermoset compositions GENERAL ELECTRIC COMPANY (US) 1999-06-09 EP disclosed
US-5834565-A FOR PRINTED CIRCUIT BOARDS GENERAL ELECTRIC COMPANY (US) 1998-11-10 US disclosed
EP-0411370-B1 Polydiorganosiloxane-polycarbonate block copolycondensates BAYER AG (DE) 1993-12-01 EP disclosed
US-5112925-A Improved adhesion of coatings to moldings BAYER AKTIENGESELLSCHAFT (DE) 1992-05-12 US disclosed
EP-0411370-A2 Polydiorganosiloxane-polycarbonate block copolycondensates BAYER AG (DE) 1991-02-06 EP disclosed