Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19200134 | 0.81 | PIK3CD (0.32) | KCNH2PARP1RENHTTHTR1A | |
| SCHEMBL17813516 | 0.80 | HTR1D (0.41) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL29844807 | 0.78 | PDE3B (0.41) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL23214142 | 0.78 | PDE3B (0.41) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL13924120 | 0.78 | PDE3B (0.39) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL12235341 | 0.77 | HTT (0.35) | RENHTTTSHRBRD4 | |
| SCHEMBL15979065 | 0.76 | KCNH2 (0.43) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL23240416 | 0.76 | PDE3B (0.37) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL14476154 | 0.76 | FGFR4 (0.40) | KCNH2PDE3BPDE3AGABRG2GABRB3 | |
| SCHEMBL764050 | 0.71 | PARP1 (0.50) | KCNH2PDE3BPDE3AGABRA5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024901-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220024901-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | KCNH2 2471/4885PDE3B 125/4885PDE3A 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.