Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 18/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | EZH1 | Q92800 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13277016 | 0.88 | EZH2 (0.80) | EZH2HDAC1HDAC6EZH1 | |
| Formic Acid SCHEMBL13277056 | 0.86 | EZH2 (0.77) | EZH2HDAC1HDAC6EZH1 | |
| SCHEMBL20612508 | 0.86 | EZH2 (0.77) | EZH2HDAC1HDAC6EZH1 | |
| SCHEMBL13277057 | 0.85 | EZH2 (0.60) | EZH2HDAC1HDAC6EZH1 | |
| SCHEMBL24224510 | 0.85 | EZH2 (0.80) | EZH2HDAC1HDAC6 | |
| SCHEMBL18400629 | 0.82 | EZH2 (0.62) | EZH2HDAC1HDAC6 | |
| SCHEMBL13277236 | 0.82 | EZH2 (0.71) | EZH2HDAC1HDAC6 | |
| SCHEMBL13277199 | 0.82 | EZH2 (0.80) | EZH2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL13277428 | 0.81 | EZH2 (0.79) | EZH2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL30687997 | 0.81 | EZH2 (0.79) | EZH2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943485-A1 | ARYL- OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |