SCHEMBL24224979

SCHEMBL24224979

C=CC(O)N[C@H]1CCCC[C@H]1Nc1ncc2c(n1)N(Cc1c[nH]cn1)C(=O)N(c1c(Cl)c(OC)cc(OC)c1Cl)C2

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17974096 0.89 FGFR4 (0.80) FGFR4
SCHEMBL16072065 0.89 FGFR4 (0.80) FGFR4
SCHEMBL23652929 0.88 FGFR4 (0.68) FGFR4
SCHEMBL23653129 0.88 FGFR4 (0.69) FGFR4
SCHEMBL19363684 0.87 FGFR4 (0.62) FGFR4
SCHEMBL21166528 0.86 FGFR4 (0.77) FGFR4
SCHEMBL19800952 0.86 FGFR4 (0.77) FGFR4
SCHEMBL17974099 0.83 FGFR4 (0.77) FGFR4
SCHEMBL19801160 0.83 FGFR4 (0.68) FGFR4
SCHEMBL23653289 0.79 FGFR4 (0.79) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3943087-A1 HETEROARYL COMPOUNDS AND USES THEREOF Celgene CAR LLC (BM) 2022-01-26 — — EP disclosed
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