SCHEMBL23652929

SCHEMBL23652929

C=CC(O)NC1CCCCC1Nc1ncc2c(n1)N(CCOC)C(=O)N(c1c(Cl)c(OC)cc(OC)c1Cl)C2

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23653129 0.91 FGFR4 (0.69) FGFR4
SCHEMBL21166528 0.90 FGFR4 (0.77) FGFR4
SCHEMBL19800952 0.90 FGFR4 (0.77) FGFR4
SCHEMBL16071393 0.88 FGFR4 (0.87) FGFR4
SCHEMBL24224979 0.88 FGFR4 (0.63) FGFR4
SCHEMBL23653289 0.82 FGFR4 (0.79) FGFR4
SCHEMBL24225235 0.82 FGFR4 (0.68) FGFR4
SCHEMBL16071621 0.81 FGFR4 (1.00) FGFR4
SCHEMBL16071628 0.80 FGFR4 (1.00) FGFR4
SCHEMBL22420144 0.80 FGFR4 (0.54) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968337-B1 HETEROARYL COMPOUNDS AND USES THEREOF CELGENE CAR LLC (BM) 2021-07-21 — — EP disclosed
Send feedback