Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680035 | 1.00 | MAPT (0.44) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL25004972 | 0.96 | MAPT (0.47) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL10657309 | 0.96 | MAPT (0.47) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL6680325 | 0.96 | MAPT (0.47) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL11613930 | 0.94 | MAPT (0.46) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL9296222 | 0.92 | MAPT (0.43) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL4511080 | 0.89 | MAPT (0.44) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL11420196 | 0.87 | MAPT (0.41) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL8729385 | 0.87 | HSD17B10 (0.45) | MAPTGPR84SPHK1FFAR1TDP1 | |
| SCHEMBL8520740 | 0.86 | MAPT (0.42) | MAPTGPR84SPHK1FFAR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202841-A1 | DERMATOLOGICAL FORMULATIONS FOR TREATMENT OF DERMATITIS | KUPETSKY ERINE A (US) | 2022-06-30 | — | — | US | claimed |
| CN-114099357-A | Hydroxytyrosol-containing polyol-in-oil nano emulsion, and preparation method and application thereof | 江苏瑞霆生物科技有限公司 | 2022-03-01 | — | — | CN | claimed |
| US-10744112-B2 | Composition comprising avermectin compounds without solvents and propenetrating agents of avermectin compounds | Nestlé Skin Health S.A. (CH) | 2020-08-18 | — | — | US | claimed |
| US-10744147-B2 | Composition comprising avermectin compounds without solid fatty substances | Nestlé Skin Health S.A. (CH) | 2020-08-18 | — | — | US | claimed |
| US-10695315-B2 | Composition comprising avermectin compounds without gelling agents | Nestlé Skin Health S.A. (CH) | 2020-06-30 | — | — | US | claimed |
| CN-104284970-A | Emulsifier composition and the use thereof | EVONIK DEGUSSA CHINA CO LTD | 2015-01-14 | — | — | CN | claimed |
| EP-1882029-B1 | STRUCTURED SURFACTANT COMPOSITIONS | SOLVAY USA INC (US) | 2014-05-07 | — | — | EP | claimed |
| WO-2013170419-A1 | EMULSIFIER COMPOSITION AND THE USE THEREOF | Evonik Degussa (China) Co., Ltd. (CN) | 2013-11-21 | — | — | WO | claimed |
| CN-102784070-A | Stable hydroquinone-containing polyol-in-oil composition and preparation method thereof | EVONIK DEGUSSA SPECIAL CHEMICAL SHANGHAI CO LTD | 2012-11-21 | — | — | CN | claimed |
| CN-101223267-B | Structured surfactant compositions | RHODIA | 2011-04-13 | — | — | CN | claimed |
| EP-1347747-B1 | METHOD FOR PREPARING SUBMICRON PARTICLE SUSPENSIONS OF PHARMACEUTICAL AGENTS | BAXTER INT (US) | 2006-03-08 | — | — | EP | claimed |
| WO-2005017134-A2 | ISOZYME OF AUTOCLAVABLE SUPEROXIDE DISMUTASE (SOD) DERIVED FROM CURCUMA LONGA L | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-02-24 | — | — | WO | claimed |
| CN-1531920-A | Sin-care composition | ���Ǿ� | 2004-09-29 | — | — | CN | claimed |
| US-20040175403-A1 | Skin moisturizing composition | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. | 2004-09-09 | — | — | US | claimed |
| EP-1454622-A1 | Skin moisturizing composition | Johnson & Johnson Consumer Companies, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| US-20030064494-A1 | Novel isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD and use of the said SOD in cosmetic, food, and pharmaceutical compositions | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2003-04-03 | — | — | US | claimed |
| CN-1404819-A | Skin-care composition changing colour when dry | JOHNSON & JOHNSON CONSUMER (US) | 2003-03-26 | — | — | CN | claimed |
| US-20030044366-A1 | Skin care composition that changes color upon drying | DOLE VICTORIA F (US) | 2003-03-06 | — | — | US | claimed |
| EP-1283032-A1 | Skin care composition that changes color upon drying | JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) | 2003-02-12 | — | — | EP | claimed |
| US-6485950-B1 | Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-11-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040175403-A1 | Skin moisturizing composition | DEGS1, COL14A1, CUTA | MAPT 3328/4885GPR84 510/4885SPHK1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.