SCHEMBL24225084

SCHEMBL24225084

C=CC(=O)N[C@H]1CCCC[C@H]1Nc1ncc2c(n1)N(Cc1ccccc1)C(O)N(c1c(Cl)c(OC)cc(OC)c1Cl)C2

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18897164 0.88 FGFR4 (0.56) FGFR4
SCHEMBL18897273 0.87 FGFR4 (0.73) FGFR4
SCHEMBL16072322 0.85 FGFR4 (1.00) FGFR4
SCHEMBL16071431 0.85 FGFR4 (1.00) FGFR4
SCHEMBL16071395 0.85 FGFR4 (1.00) FGFR4
SCHEMBL24225091 0.84 FGFR4 (0.53) FGFR4
SCHEMBL19363703 0.83 FGFR4 (0.64) FGFR4
SCHEMBL19363690 0.83 FGFR4 (0.62) FGFR4
SCHEMBL19363630 0.82 FGFR4 (0.67) FGFR4
SCHEMBL24224985 0.82 FGFR4 (0.68) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3943087-A1 HETEROARYL COMPOUNDS AND USES THEREOF Celgene CAR LLC (BM) 2022-01-26 — — EP disclosed
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