Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24225084 | 0.88 | FGFR4 (0.73) | FGFR4 | |
| SCHEMBL22420144 | 0.87 | FGFR4 (0.54) | FGFR4 | |
| SCHEMBL18897171 | 0.79 | FGFR4 (0.46) | FGFR4 | |
| SCHEMBL22420164 | 0.78 | FGFR4 (0.43) | FGFR4 | |
| SCHEMBL21166528 | 0.78 | FGFR4 (0.77) | FGFR4 | |
| SCHEMBL19800952 | 0.78 | FGFR4 (0.77) | FGFR4 | |
| SCHEMBL23653274 | 0.77 | FGFR4 (0.66) | FGFR4 | |
| SCHEMBL23653129 | 0.77 | FGFR4 (0.69) | FGFR4 | |
| SCHEMBL23652929 | 0.76 | FGFR4 (0.68) | FGFR4 | |
| SCHEMBL24224979 | 0.74 | FGFR4 (0.63) | FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663524-B2 | Substituted pyrido[2,3-d]pyrimidines as protein kinase inhibitors | CELGENE CAR LLC (BM) | 2017-05-30 | — | — | US | disclosed |