Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071680 | 0.81 | FGFR4 (0.65) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL21860422 | 0.79 | FGFR4 (0.49) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071525 | 0.77 | FGFR4 (0.75) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18897357 | 0.74 | FGFR1 (0.65) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16071414 | 0.74 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL20734003 | 0.74 | FGFR4 (0.56) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24225223 | 0.73 | FGFR4 (0.49) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL21860424 | 0.73 | FGFR4 (0.52) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL21166428 | 0.71 | FGFR4 (0.63) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL22337440 | 0.70 | TNK2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |