Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 19/20 | 0.68 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166528 | 0.92 | FGFR4 (0.77) | FGFR4FGFR1 | |
| SCHEMBL19800952 | 0.92 | FGFR4 (0.77) | FGFR4FGFR1 | |
| SCHEMBL19363574 | 0.88 | FGFR4 (0.84) | FGFR4FGFR1 | |
| SCHEMBL16071498 | 0.88 | FGFR4 (0.84) | FGFR4FGFR1 | |
| SCHEMBL23653305 | 0.88 | FGFR4 (0.64) | FGFR4FGFR1 | |
| SCHEMBL24224914 | 0.87 | FGFR4 (0.80) | FGFR4FGFR1 | |
| SCHEMBL18897120 | 0.86 | FGFR4 (0.69) | FGFR4FGFR1 | |
| SCHEMBL23652929 | 0.82 | FGFR4 (0.68) | FGFR4 | |
| SCHEMBL23653129 | 0.81 | FGFR4 (0.69) | FGFR4 | |
| SCHEMBL16071603 | 0.81 | FGFR4 (1.00) | FGFR4FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |