⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL28195185 | 0.97 | CA2 (0.52) | — | |
| SCHEMBL28709291 | 0.97 | CA2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL27640046 | 0.97 | CA2 (0.52) | — | |
| Water SCHEMBL15152290 | 0.97 | CA2 (0.52) | — | |
| Hydrochloric Acid SCHEMBL956960 | 0.97 | CA2 (0.52) | — | |
| SCHEMBL28848380 | 0.97 | CA2 (0.52) | — | |
| SCHEMBL28706408 | 0.97 | CA2 (0.52) | — | |
| SCHEMBL21065355 | 0.97 | CA2 (0.52) | — | |
| Bromide SCHEMBL21957301 | 0.97 | CA2 (0.52) | — | |
| SCHEMBL8029418 | 0.97 | CA2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3942 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100410-B1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES INC (US) | 2026-04-22 | — | — | EP | claimed |
| EP-4301736-B1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2025-10-08 | — | — | EP | claimed |
| EP-4619106-A2 | TREATMENT OF ASCT2-DEPENDENT CANCERS | Neupharma, Inc (US) | 2025-09-24 | — | — | EP | claimed |
| US-12344600-B2 | c-Myc mRNA translation modulators and uses thereof in the treatment of cancer | ANIMA BIOTECH INC. (US) | 2025-07-01 | — | — | US | claimed |
| CN-118005609-B | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2025-06-17 | — | — | CN | claimed |
| EP-4554569-A1 | AGENT CONTAINING MALONIC ACID OR ITS DERIVATIVES FOR RESTORING METAL HOMEOSTASIS | Oxford Antibiotic Group GmbH (AT) | 2025-05-21 | — | — | EP | claimed |
| CN-117800942-B | Thiophene piperazine amide derivative, composition and application thereof | 徐州医科大学 | 2025-04-25 | — | — | CN | claimed |
| CN-119866217-A | Agent for restoring metal steady state containing malonic acid or derivative thereof | 牛津抗生素(制药)集团股份有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-119816492-A | TRPV2 channel blocker and use thereof | 伊契洛夫科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| US-20250109128-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2025-04-03 | — | — | US | claimed |
| WO-1985000811-A1 | NOVEL 1-PIPERAZINECARBOXAMIDE DERIVATIVES | AB FERROSAN (SE) | 1985-02-28 | — | — | WO | claimed |
| EP-0099686-A2 | Process for preparing polypiperazinamide anisotropic membranes | Montedison S.p.A. (IT) | 1984-02-01 | — | — | EP | claimed |
| US-4416817-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-22 | — | — | US | claimed |
| US-4269838-A | ADRENERGIC BLOCKING AGENTS; ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4161586-A | 5-Hydroxy-PGI1 piperazinylamides | THE UPJOHN COMPANY (US) | 1979-07-17 | — | — | US | claimed |
| US-4137403-A | 9-Deoxy-9-methylene-PGF2 cycloamides | THE UPJOHN COMPANY (US) | 1979-01-30 | — | — | US | claimed |
| US-4124704-A | ANTIMICROBIAL | RIKER LABORATORIES, INC. (US) | 1978-11-07 | — | — | US | claimed |
| US-4123424-A | Polymeric piperazinamides and membranes for reverse osmosis made therefrom | MONTEDISON S.P.A. (IT) | 1978-10-31 | — | — | US | claimed |
| US-4067993-A | Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids | RIKER LABORATORIES, INC. (US) | 1978-01-10 | — | — | US | claimed |
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | claimed |