Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24227449 | 0.84 | ALDH1A1 (0.52) | ALDH1A1PRMT5MEN1KMT2ARAB9A | |
| SCHEMBL24227433 | 0.81 | PRMT5 (0.57) | ALDH1A1PRMT5MEN1KMT2ANPC1 | |
| SCHEMBL24227441 | 0.80 | ALDH1A1 (0.48) | ALDH1A1PRMT5MEN1KMT2ARAB9A | |
| SCHEMBL17560261 | 0.80 | PRMT5 (0.59) | ALDH1A1PRMT5MEN1KMT2ARAB9A | |
| SCHEMBL17572107 | 0.80 | CYP1A2 (0.60) | ALDH1A1PRMT5MEN1KMT2ANPC1 | |
| SCHEMBL19836092 | 0.79 | MEN1 (0.58) | ALDH1A1PRMT5MEN1KMT2ANPC1 | |
| SCHEMBL15087817 | 0.79 | MEN1 (0.58) | ALDH1A1PRMT5MEN1KMT2ANPC1 | |
| SCHEMBL19835585 | 0.79 | MEN1 (0.58) | ALDH1A1PRMT5MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL19518472 | 0.78 | MEN1 (0.61) | ALDH1A1PRMT5MEN1KMT2ANPC1 | |
| SCHEMBL17572103 | 0.77 | PRMT5 (0.54) | ALDH1A1PRMT5MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3945091-A1 | NOVEL VDAC1 INHIBITORS | Abarceo AB (SE) | 2022-02-02 | — | — | EP | disclosed |