⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648660 | 1.00 | — | — | |
| SCHEMBL26297461 | 1.00 | — | — | |
| SCHEMBL22926 | 0.77 | — | — | |
| SCHEMBL28893506 | 0.77 | GGT1 (0.50) | — | |
| SCHEMBL2354822 | 0.77 | — | — | |
| SCHEMBL23240782 | 0.77 | — | — | |
| SCHEMBL161672 | 0.77 | — | — | |
| SCHEMBL28893505 | 0.77 | GGT1 (0.50) | — | |
| SCHEMBL26670507 | 0.77 | — | — | |
| SCHEMBL25788599 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023066292-A1 | TRICYCLIC BORONIC ACID DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海济煜医药科技有限公司 | 2023-04-27 | — | — | WO | disclosed |
| WO-2022023723-A1 | GLP-1 RECEPTOR ANTAGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-02-03 | — | — | WO | disclosed |