Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24365042 | 0.86 | AAK1 (0.36) | AAK1LOXL2LIPG | |
| SCHEMBL30469929 | 0.86 | AAK1 (0.36) | AAK1LOXL2LIPG | |
| SCHEMBL29980920 | 0.84 | AAK1 (0.41) | AAK1LOXL2LIPG | |
| SCHEMBL25322756 | 0.83 | AAK1 (0.34) | AAK1LOXL2LIPG | |
| SCHEMBL25322762 | 0.83 | AAK1 (0.34) | AAK1LOXL2LIPG | |
| SCHEMBL30470940 | 0.83 | AAK1 (0.36) | AAK1LIPG | |
| SCHEMBL24364958 | 0.83 | AAK1 (0.36) | AAK1LIPG | |
| SCHEMBL31136351 | 0.77 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL24363782 | 0.77 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL24365876 | 0.77 | RAB9A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022026892-A1 | PIPERIDIN-1- YL-N-PYRYDI NE-3-YL-2-OXOACET AM IDE DERIVATIVES USEFUL FOR THE TREATMENT OF MTAP-DEFICIENT AND/OR MT A-ACCUMULATING CANCERS | TANGO THERAPEUTICS, INC. (US) | 2022-02-03 | — | — | WO | disclosed |