Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.52 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.52 |
| ▸ | DTYMK | P23919 | 4/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 7/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18521023 | 1.00 | POLB (0.56) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18521172 | 1.00 | POLB (0.56) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18510961 | 0.94 | ADORA1 (0.58) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18521030 | 0.94 | ADORA1 (0.58) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18521014 | 0.93 | POLB (0.58) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18510903 | 0.93 | POLB (0.58) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18521007 | 0.93 | POLB (0.58) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18521233 | 0.92 | POLB (0.57) | POLBP2RY2P2RY4P2RY6F2 | |
| SCHEMBL25818243 | 0.92 | P2RY2 (0.52) | POLBP2RY2P2RY4P2RY6DTYMK | |
| SCHEMBL18520860 | 0.91 | POLB (0.51) | POLBP2RY2P2RY4P2RY6DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033435-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | MERCK SHARP & DOHME CORP. (US) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033435-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | STING1, CGAS, IFNAR1 | POLB 330/4885P2RY2 71/4885P2RY4 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.