Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.52 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.52 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 12/20 | 0.49 |
| ▸ | DTYMK | P23919 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619364 | 0.92 | P2RY2 (0.53) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL23619493 | 0.92 | P2RY2 (0.53) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL18521023 | 0.92 | POLB (0.56) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL18521172 | 0.92 | POLB (0.56) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL24239208 | 0.92 | POLB (0.56) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL18511009 | 0.92 | P2RY2 (0.52) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL22381511 | 0.92 | P2RY2 (0.52) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL18522005 | 0.92 | P2RY2 (0.52) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL23619431 | 0.91 | STING1 (0.45) | P2RY2P2RY4P2RY6POLBF2 | |
| SCHEMBL18511043 | 0.90 | NT5E (0.49) | STING1NT5ETAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | MERCK SHARP & DOHME LLC (US) | 2023-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685761-B2 | Cyclic di-nucleotide compounds as sting agonists | STING1, CGAS, IFNAR1 | P2RY2 79/4885P2RY4 163/4885P2RY6 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.