SCHEMBL24239386

SCHEMBL24239386

CNN(C)NCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
IDO1 P14902 2/20 0.43
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TAAR1 Q96RJ0 2/20 0.40
ATM Q13315 1/20 0.40
AOC3 Q16853 1/20 0.40
CALM1 P0DP23 1/20 0.40
HTT P42858 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39
ADH1A P07327 1/20 0.39
ADH7 P40394 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL342670 0.79 CYP3A4 (0.52) CYP3A4MAPTKDM4EIDO1ALDH1A1
Hydrochloric Acid SCHEMBL5162000 0.77 MAPT (0.56) CYP3A4MAPTKDM4EIDO1ALDH1A1
SCHEMBL16735543 0.76 IDO1 (0.50) CYP3A4MAPTKDM4EIDO1ALDH1A1
SCHEMBL24239349 0.76 AOC3 (0.52) CYP3A4MAPTKDM4EIDO1ALDH1A1
SCHEMBL14797789 0.74 CYP3A4 (0.46) CYP3A4MAPTKDM4EIDO1ALDH1A1
SCHEMBL8215112 0.74 TSHR (0.54) CYP3A4MAPTKDM4EIDO1ALDH1A1
SCHEMBL8854666 0.73 CYP3A4 (0.50) CYP3A4MAPTKDM4EIDO1ALDH1A1
Hydrochloric Acid SCHEMBL607788 0.72 ALDH1A1 (0.52) CYP3A4MAPTKDM4EIDO1ALDH1A1
Ethylbenzene SCHEMBL27988415 0.72 TP53 (0.58) CYP3A4MAPTKDM4EIDO1ALDH1A1
Trimethylammonium SCHEMBL27861478 0.72 MEN1 (0.64) CYP3A4MAPTKDM4EIDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220033363-A1 HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES BAYER AKTIENGESELLSCHAFT (DE) 2022-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033363-A1 HERBICIDALLY ACTIVE SUBSTITUTED PHENYLPYRIMIDINE HYDRAZIDES DDT, CBR3, CAT CYP3A4 239/4885MAPT 4487/4885KDM4E 1422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.