SCHEMBL2423979

SCHEMBL2423979

Clc1cc(C(Cl)(Cl)Cl)nc(Cl)n1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
CYP3A4 P08684 1/20 0.43
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
LMNA P02545 1/20 0.33
S1PR2 O95136 1/20 0.32
ATF1 P18846 1/20 0.31
NFKB1 P19838 1/20 0.31
HRH4 Q9H3N8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10555728 0.81 ATF1 (0.33) TSHRCYP3A4ALDH1A1ALOX15ATF1
SCHEMBL10558546 0.81 ATF1 (0.33) TSHRCYP3A4ALDH1A1ALOX15ATF1
SCHEMBL2721824 0.78 HRH4 (0.49) TSHRALDH1A1ALOX15LMNAHRH4
SCHEMBL29438115 0.78 HRH4 (0.49) TSHRALDH1A1ALOX15LMNAHRH4
SCHEMBL628056 0.78 NT5E (0.39) TSHRCYP3A4ALDH1A1ALOX15ATF1
SCHEMBL11116149 0.76 CYP3A4 (0.40) TSHRCYP3A4S1PR2
SCHEMBL26685429 0.76 HRH4 (0.36) TSHRALDH1A1ALOX15LMNAATF1
SCHEMBL30632784 0.76 HRH4 (0.36) TSHRALDH1A1ALOX15LMNAATF1
SCHEMBL9722826 0.76 KMT2A (0.47) TSHRCYP3A4ALDH1A1LMNAHRH4
SCHEMBL10745556 0.76 CYP3A4 (0.40) TSHRCYP3A4S1PR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213663-B1 Preparation of halogenated N-heteroaromatic polyhalogen derivatives SALTIGO GMBH (DE) 2011-09-28 EP claimed
EP-2213663-A1 Preparation of halogenated N-heteroaromatic polyhalogen derivatives Saltigo GmbH (DE) 2010-08-04 EP claimed
EP-2213663-B1 Preparation of halogenated N-heteroaromatic polyhalogen derivatives SALTIGO GMBH (DE) 2011-09-28 EP disclosed
EP-2213663-A1 Preparation of halogenated N-heteroaromatic polyhalogen derivatives Saltigo GmbH (DE) 2010-08-04 EP disclosed
US-6235904-B1 VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. BASF AKTIENGESELLSCHAFT (DE) 2001-05-22 US disclosed
EP-0572429-B1 SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF BASF AG (DE) 2001-04-18 EP disclosed
EP-1068390-A1 METHOD FOR IMPROVED WET STRENGTH PAPER Kimberly-Clark Worldwide, Inc. (US) 2001-01-17 EP disclosed
WO-1999045201-A1 METHOD FOR IMPROVED WET STRENGTH PAPER KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-09-10 WO disclosed
US-5935383-A Method for improved wet strength paper KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-08-10 US disclosed
US-5591694-A COMPOUND USED TO CONTROL UNDESIRABLE PLANT GROWTH BASF AKTIENGESELLSCHAFT (DE) 1997-01-07 US disclosed
EP-0446743-B1 Herbicidal sulfonylureas, process for their preparation and intermediates BASF AG (DE) 1995-08-02 EP disclosed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4001205-A WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-4001203-A Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed
US-3956263-A 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs CIBA-GEIGY AG (CH) 1976-05-11 US disclosed