Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ATF1 | P18846 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468496 | 0.87 | NT5E (0.42) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL26685429 | 0.84 | HRH4 (0.36) | ALDH1A1ATF1NFKB1TSHRCYP2C19 | |
| SCHEMBL10558546 | 0.84 | ATF1 (0.33) | ALDH1A1ATF1NFKB1TSHRCYP3A4 | |
| SCHEMBL30632784 | 0.84 | HRH4 (0.36) | ALDH1A1ATF1NFKB1TSHRCYP2C19 | |
| SCHEMBL10555728 | 0.84 | ATF1 (0.33) | ALDH1A1ATF1NFKB1TSHRCYP3A4 | |
| SCHEMBL30809049 | 0.82 | HRH4 (0.35) | ATF1NFKB1CYP2C19 | |
| SCHEMBL113146 | 0.82 | HRH4 (0.35) | ATF1NFKB1CYP2C19 | |
| SCHEMBL6294671 | 0.79 | NT5E (0.38) | NT5EALDH1A1KDM4EHSD17B10HSP90AA1 | |
| SCHEMBL2423979 | 0.78 | TSHR (0.43) | ALDH1A1ATF1NFKB1TSHRCYP3A4 | |
| SCHEMBL16280022 | 0.78 | PDE4D (0.42) | ALDH1A1KDM4EHSD17B10ATF1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110951051-B | Preparation method and application of thermotropic delayed fluorescence copolymer with side chain containing trifluoromethyl pyrimidine | 大连理工大学 | 2021-04-20 | — | — | CN | claimed |
| CN-110951051-A | Preparation method and application of thermotropic delayed fluorescence copolymer with side chain containing trifluoromethyl pyrimidine | 大连理工大学 | 2020-04-03 | — | — | CN | claimed |
| EP-2213663-B1 | Preparation of halogenated N-heteroaromatic polyhalogen derivatives | SALTIGO GMBH (DE) | 2011-09-28 | — | — | EP | claimed |
| EP-2213663-A1 | Preparation of halogenated N-heteroaromatic polyhalogen derivatives | Saltigo GmbH (DE) | 2010-08-04 | — | — | EP | claimed |
| US-12637436-B2 | Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2026-05-26 | — | — | US | disclosed |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | LG CHEM, LTD. (KR) | 2026-05-26 | — | — | US | disclosed |
| US-12630528-B2 | Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof | LG CHEM, LTD. (KR) | 2026-05-19 | — | — | US | disclosed |
| EP-4731623-A1 | CARBOLINE COMPOUNDS AND USE THEREOF | PTC Therapeutics, Inc. (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12611401-B2 | Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases | PFIZER INC. (US) | 2026-04-28 | — | — | US | disclosed |
| EP-4695239-A1 | DISUBSTITUTED PYRIMIDINE COMPOUNDS FOR KETOHEXOKINASE INHIBITION | Centennial Therapeutics, LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20260035367-A1 | PKC-Theta Modulators | CELGENE CORPORATION (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4685141-A1 | ISOINDOLINE DERIVATIVE, BENZOINDOLE DERIVATIVE AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-28 | — | — | EP | disclosed |
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-22 | — | — | US | disclosed |
| WO-2008046757-A1 | AMINOMETHYL-4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-24 | — | — | WO | disclosed |
| US-20060172994-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006071875-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | WO | disclosed |
| US-4877443-A | 2,4-diamino-6-trifluoromethylpyrimidine compounds useful as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-31 | — | — | US | disclosed |
| EP-0230244-A2 | 2,4-Diamino-6-halogenoalkyl pyrimidines | BAYER AG (DE) | 1987-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093480-A1 | INSECTICIDAL PYRIMIDINYL ARYL HYRDRAZONES | DDT, HELZ, HPD | NT5E 3363/4885ALDH1A1 802/4885KDM4E 2517/4885 |
| US-20060172994-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | NT5E 570/4885ALDH1A1 1901/4885KDM4E 4645/4885 |
| US-20260035367-A1 | PKC-Theta Modulators | PRKAR2B, PRKAR2A, PRKCD | NT5E 4105/4885ALDH1A1 4459/4885KDM4E 4598/4885 |
| US-20080119535-A1 | AMINOMETHYL-4-IMIDAZOLES | INMT, HTR4, MC4R | NT5E 3185/4885ALDH1A1 631/4885KDM4E 69/4885 |
| US-12630528-B2 | Amino aryl derivative useful as diacylglycerol acyltransferase 2 inhibitor and use thereof | DGAT2, DGAT1, SOAT2 | NT5E 3672/4885ALDH1A1 597/4885KDM4E 2839/4885 |
| US-12611401-B2 | Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases | GLP1R, GCKR, GPR119 | NT5E 3646/4885ALDH1A1 743/4885KDM4E 899/4885 |
| US-12637440-B2 | Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof | DGAT2, DGAT1, DLAT | NT5E 3162/4885ALDH1A1 885/4885KDM4E 3064/4885 |
| US-12637436-B2 | Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof | GRM3, GRM2, GRM1 | NT5E 2267/4885ALDH1A1 3385/4885KDM4E 1949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.