Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 13/20 | 0.80 |
| ▸ | KDR | P35968 | 5/20 | 0.80 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.80 |
| ▸ | RET | P07949 | 3/20 | 0.80 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.80 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.80 |
| ▸ | FLT1 | P17948 | 3/20 | 0.80 |
| ▸ | FLT4 | P35916 | 3/20 | 0.80 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.80 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.80 |
| ▸ | KIT | P10721 | 2/20 | 0.80 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.80 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.80 |
| ▸ | ERN1 | O75460 | 1/20 | 0.80 |
| ▸ | STK10 | O94804 | 1/20 | 0.80 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.80 |
| ▸ | ABL1 | P00519 | 1/20 | 0.80 |
| ▸ | ESR1 | P03372 | 1/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.80 |
| ▸ | BCR | P11274 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22521219 | 0.92 | FGFR4 (0.77) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL22521247 | 0.92 | FGFR4 (0.77) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL1899046 | 0.91 | FGFR4 (0.81) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL864029 | 0.91 | FGFR4 (0.80) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL864156 | 0.91 | FGFR4 (0.85) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL864110 | 0.91 | FGFR4 (0.82) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL22521245 | 0.90 | FGFR4 (0.74) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL22521206 | 0.90 | FGFR4 (0.74) | FGFR4KDRFGFR1RETPDGFRB | |
| SCHEMBL12412057 | 0.90 | FGFR4 (0.76) | FGFR4KDRFGFR1RETPDGFRB | |
| Lenvatinib SCHEMBL29349806 | 0.89 | FGFR4 (1.00) | FGFR4KDRFGFR1RETPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950677-A1 | QUINOLYL-CONTAINING COMPOUND AND PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Primegene (Beijing) Co., Ltd. (CN) | 2022-02-09 | — | — | EP | disclosed |