Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27230 | 0.87 | TSHR (0.48) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL9620366 | 0.80 | TSHR (0.42) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL24241946 | 0.79 | GAA (0.50) | TSHRTDP1MGAMGAASI | |
| SCHEMBL3193802 | 0.78 | TSHR (0.41) | TSHRTDP1MGAMGAASI | |
| SCHEMBL15382406 | 0.78 | TSHR (0.41) | TSHRTDP1MGAMGAASI | |
| SCHEMBL24242028 | 0.78 | MGAM (0.48) | TSHRTDP1MGAMGAASI | |
| SCHEMBL9738888 | 0.77 | TSHR (0.39) | TSHRTDP1MGAMGAASI | |
| SCHEMBL8063540 | 0.77 | TSHR (0.39) | TSHRTDP1MGAMGAASI | |
| SCHEMBL25602863 | 0.76 | MGAM (0.44) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL24242139 | 0.75 | LMNA (0.38) | TSHRMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728235-B1 | SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-09 | — | — | EP | disclosed |