Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 9/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.48 |
| ▸ | KDM5A | P29375 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604627 | 0.90 | PHF8 (0.69) | PHF8KDM2BKDM4CKDM5AKDM2A | |
| SCHEMBL17604664 | 0.88 | PHF8 (0.72) | PHF8KDM2BKDM4CKDM5AKDM2A | |
| SCHEMBL17604620 | 0.88 | KDM4C (0.57) | PHF8KDM2BKDM4CKDM5AKDM2A | |
| SCHEMBL17604577 | 0.85 | PHF8 (0.73) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL29376220 | 0.85 | PHF8 (0.73) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL17604566 | 0.82 | KDM4C (0.70) | PHF8KDM2BKDM4CKDM5AKDM2A | |
| SCHEMBL17604626 | 0.81 | KDM4C (0.69) | PHF8KDM2BKDM4CKDM5AKDM2A | |
| SCHEMBL20101115 | 0.80 | PHF8 (0.70) | PHF8KDM2BKDM4CKDM5AKDM5B | |
| SCHEMBL17686567 | 0.80 | KDM4C (0.73) | PHF8KDM2BKDM4CKDM5AKDM2A | |
| SCHEMBL24244135 | 0.78 | KDM4C (0.58) | PHF8KDM2BKDM4CKDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |