Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629155 | 0.71 | ALDH1A1 (0.37) | POLBALDH1A1 | |
| SCHEMBL10304437 | 0.71 | ALDH1A1 (0.37) | POLBALDH1A1 | |
| SCHEMBL10304510 | 0.71 | ALDH1A1 (0.37) | POLBALDH1A1 | |
| SCHEMBL9858652 | 0.69 | — | — | |
| SCHEMBL1488846 | 0.69 | CHRNA7 (0.33) | — | |
| SCHEMBL17077882 | 0.68 | — | — | |
| SCHEMBL18758303 | 0.67 | NEK2 (0.36) | — | |
| SCHEMBL12233131 | 0.65 | CHRNA7 (0.33) | — | |
| SCHEMBL24059764 | 0.64 | ALDH1A1 (0.38) | ALDH1A1HPGD | |
| SCHEMBL20355341 | 0.62 | CHRNA7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567030-B1 | QUINAZOLINE COMPOUND FOR EGFR INHIBITION | MEDSHINE DISCOVERY INC (CN) | 2022-02-09 | — | — | EP | disclosed |