Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204609 | 0.84 | LMNA (0.54) | LMNAMGLLSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL15165818 | 0.83 | LMNA (0.45) | LMNAMGLLSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8393585 | 0.79 | EPHX1 (0.58) | LMNAMGLLEPHX1ALDH1A1NAAA | |
| SCHEMBL8392638 | 0.79 | EPHX1 (0.58) | LMNAMGLLEPHX1ALDH1A1NAAA | |
| SCHEMBL8393587 | 0.77 | EPHX1 (0.55) | LMNAMGLLEPHX1ALDH1A1NAAA | |
| SCHEMBL20844590 | 0.76 | LMNA (0.52) | LMNAPARP15PARP10MGLLSLC1A3 | |
| SCHEMBL8396762 | 0.75 | LMNA (0.55) | LMNAPARP15PARP10SLC1A3SLC1A2 | |
| SCHEMBL562319 | 0.75 | LMNA (0.55) | LMNAPARP15PARP10SLC1A3SLC1A2 | |
| SCHEMBL17550878 | 0.75 | LMNA (0.47) | LMNAMGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL206033 | 0.74 | PTGIR (0.45) | LMNASLC1A3SLC1A2SLC1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950004-A1 | TARGETED COMPOSITIONS | Arbutus Biopharma Corporation (CA) | 2022-02-09 | — | — | EP | disclosed |