SCHEMBL24245804

SCHEMBL24245804

c1ccc(-c2nc3ccccc3nc2-n2c3ccc4ccc5ccc6ccc7ccc8ccc2c2c8c7c6c5c4c23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.48
CASP1 P29466 2/20 0.48
HRH4 Q9H3N8 1/20 0.48
KDM4E B2RXH2 7/20 0.43
PKM P14618 1/20 0.43
ALDH1A1 P00352 5/20 0.43
GAA P10253 3/20 0.43
HPGD P15428 1/20 0.43
L3MBTL1 Q9Y468 5/20 0.42
LMNA P02545 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
HTT P42858 2/20 0.42
AKT1 P31749 1/20 0.37
AKT2 P31751 1/20 0.37
POLB P06746 1/20 0.37
PDE10A Q9Y233 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24245672 0.92 HSD17B10 (0.42) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL24245522 0.90 HSD17B10 (0.41) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL24245674 0.89 CASP1 (0.40) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL24245817 0.89 HSD17B10 (0.40) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL23874825 0.88 HSD17B10 (0.49) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL22989116 0.87 CASP1 (0.44) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL24245656 0.87 CASP1 (0.39) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL24245815 0.87 HSD17B10 (0.39) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL22988940 0.86 CASP1 (0.40) HSD17B10CASP1HRH4KDM4EPKM
SCHEMBL21366912 0.86 HSD17B10 (0.40) HSD17B10CASP1HRH4KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220045281-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220045281-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, ICOSLG, OR10J3 HSD17B10 2940/4885CASP1 1016/4885HRH4 4533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.