⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198445 | 0.83 | — | — | |
| Glycine SCHEMBL15145247 | 0.78 | GLRA1 (0.48) | — | |
| SCHEMBL23921626 | 0.78 | KMT2A (0.39) | — | |
| SCHEMBL14701560 | 0.75 | DPP4 (0.33) | — | |
| SCHEMBL24042636 | 0.75 | — | — | |
| SCHEMBL11915757 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL1378572 | 0.74 | — | — | |
| SCHEMBL14450656 | 0.73 | DPP4 (0.32) | — | |
| SCHEMBL18025340 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5724130 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11242323-B2 | Inhibition of OLIG2 activity | Curtana Pharmaceuticals, Inc. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20130178437-A1 | CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-11 | — | — | US | disclosed |