⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18576168 | 0.92 | KDM4E (0.30) | — | |
| SCHEMBL11315890 | 0.79 | KDM4E (0.33) | — | |
| SCHEMBL11081460 | 0.78 | — | — | |
| SCHEMBL401494 | 0.78 | — | — | |
| SCHEMBL5406504 | 0.78 | — | — | |
| SCHEMBL2866356 | 0.74 | — | — | |
| SCHEMBL8199466 | 0.74 | USP2 (0.33) | — | |
| SCHEMBL27898571 | 0.71 | — | — | |
| SCHEMBL2436914 | 0.71 | KDM4E (0.31) | — | |
| SCHEMBL24450286 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49934-E1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2024-04-23 | — | — | US | disclosed |
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11325914-B1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2022-05-10 | — | — | US | disclosed |
| CN-108558673-B | Method for producing 2- (1-cyclohexenyl) ethylamine | 上海泾维化工科技有限公司 | 2021-03-16 | — | — | CN | disclosed |
| US-10800782-B2 | Inhibitors of cellular metabolic processes | Agios Pharmaceutical, Inc. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190233424-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2019-08-01 | — | — | US | disclosed |
| EP-3507290-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | Agios Pharmaceuticals, Inc. (US) | 2019-07-10 | — | — | EP | disclosed |
| US-10329298-B2 | Inhibitors of cellular metabolic processes | AGIOS PHARMACEUTICALS, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| CN-109890822-A | INHIBITORS OF CELLULAR METABOLIC PROCESSES | 安吉奥斯医药品有限公司 | 2019-06-14 | — | — | CN | disclosed |
| US-20180079753-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2018-03-22 | — | — | US | disclosed |
| WO-2018045071-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | AGIOS PHARMACEUTICALS, INC. (US) | 2018-03-08 | — | — | WO | disclosed |
| US-8222198-B2 | Perfuming nitriles | FIRMENICH SA (CH) | 2012-07-17 | — | — | US | disclosed |
| CN-101657183-B | perfuming nitriles | FIRMENICH S.A. (CH) | 2011-12-28 | — | — | CN | disclosed |
| EP-2134318-B1 | PERFUMING NITRILES | FIRMENICH & CIE (CH) | 2011-09-07 | — | — | EP | disclosed |
| US-20110039981-A1 | EPOXY RESINS DERIVED FROM NON-SEED OIL BASED ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES LLC | 2011-02-17 | — | — | US | disclosed |
| US-20100267607-A1 | PERFUMING NITRILES | FIRMENICH SA (CH) | 2010-10-21 | — | — | US | disclosed |
| CN-101657183-A | perfuming nitriles | FIRMENICH & CIE CH | 2010-02-24 | — | — | CN | disclosed |
| EP-2134318-A1 | PERFUMING NITRILES | Firmenich S.A. (CH) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008117254-A1 | PERFUMING NITRILES | FIRMENICH SA (CH) | 2008-10-02 | — | — | WO | disclosed |