Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GMPS | P49915 | 2/20 | 0.81 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | RNF4 | P78317 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31318106 | 0.89 | GMPS (1.00) | GMPSHTTMITFALDH1A1POLB | |
| SCHEMBL21810993 | 0.89 | GMPS (1.00) | GMPSHTTMITFALDH1A1POLB | |
| SCHEMBL31318110 | 0.89 | GMPS (0.91) | GMPSHTTMITFALDH1A1POLB | |
| SCHEMBL24249569 | 0.89 | GMPS (0.91) | GMPSHTTMITFALDH1A1POLB | |
| SCHEMBL20704575 | 0.75 | GMPS (0.54) | GMPSMAOBKMT2ARAB9A | |
| SCHEMBL9154356 | 0.75 | MAOB (0.59) | GMPSMAOBSMN1; SMN2KMT2A | |
| SCHEMBL21811226 | 0.74 | GMPS (1.00) | GMPSEGFR | |
| SCHEMBL31237420 | 0.74 | GMPS (1.00) | GMPSEGFR | |
| SCHEMBL16363804 | 0.74 | SMN1; SMN2 (0.60) | GMPSALDH1A1MAOBHSD17B10MAPT | |
| SCHEMBL30180733 | 0.73 | NR4A2 (0.59) | GMPSMAOBKMT2ANR1H4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048866-A1 | NOVEL INHIBITORS OF GUANOSINE MONOPHOSPHATE SYNTHETASE AS THERAPEUTIC AGENTS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048866-A1 | NOVEL INHIBITORS OF GUANOSINE MONOPHOSPHATE SYNTHETASE AS THERAPEUTIC AGENTS | GMPS, CGAS, STING1 | GMPS 1/4885HTT 4400/4885MITF 3326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.