Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 14/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.65 |
| ▸ | KDR | P35968 | 4/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | BCR | P11274 | 10/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.55 |
| ▸ | KIT | P10721 | 7/20 | 0.55 |
| ▸ | PLK4 | O00444 | 1/20 | 0.55 |
| ▸ | DDX3X | O00571 | 1/20 | 0.55 |
| ▸ | GAK | O14976 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29551037 | 0.88 | ABL1 (0.69) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL24251159 | 0.88 | ABL1 (0.69) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL24250967 | 0.87 | PDGFRA (0.62) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL29551797 | 0.87 | PDGFRA (0.62) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL24251148 | 0.82 | ABL1 (0.65) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL29551707 | 0.82 | ABL1 (0.65) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL4897520 | 0.82 | ABL1 (0.67) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL3716810 | 0.81 | ABL1 (0.73) | ABL1PDGFRBKDRHDAC3HDAC4 | |
| SCHEMBL1927769 | 0.81 | ABL1 (0.61) | ABL1PDGFRBKDRBCRPDGFRA | |
| SCHEMBL4082083 | 0.81 | ABL1 (0.75) | ABL1PDGFRBKDRHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048893-A1 | Compounds for Treating Neurodegenerative Diseases and Cancers | HONGYI & ASS LLC (US) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048893-A1 | Compounds for Treating Neurodegenerative Diseases and Cancers | SNCA, NGF, SLC18A2 | ABL1 695/4885PDGFRB 124/4885KDR 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.