Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.69 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26474195 | 0.89 | EGFR (0.65) | EGFRALKKCNH2EML4 | |
| SCHEMBL19089313 | 0.89 | EGFR (0.72) | EGFRALKKCNH2EML4 | |
| SCHEMBL18369598 | 0.86 | EGFR (0.62) | EGFR | |
| SCHEMBL17346746 | 0.86 | EGFR (0.76) | EGFRALKKCNH2EML4 | |
| SCHEMBL17346585 | 0.86 | EGFR (0.65) | EGFRALKKCNH2 | |
| SCHEMBL17346739 | 0.86 | EGFR (0.65) | EGFRALK | |
| SCHEMBL17346734 | 0.86 | EGFR (0.75) | EGFRALKKCNH2 | |
| SCHEMBL17346644 | 0.85 | EGFR (0.65) | EGFRALKEML4 | |
| SCHEMBL17346658 | 0.85 | EGFR (0.67) | EGFRALKKCNH2 | |
| SCHEMBL29943629 | 0.85 | EGFR (0.62) | EGFRALKKCNH2EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033455-A1 | TRIAZINE DERIVATIVE HAVING EGFR INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |