Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.57 |
| ▸ | EGFR | P00533 | 11/20 | 0.57 |
| ▸ | ABL1 | P00519 | 10/20 | 0.57 |
| ▸ | KDR | P35968 | 8/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.57 |
| ▸ | HCK | P08631 | 7/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.57 |
| ▸ | MTOR | P42345 | 7/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.57 |
| ▸ | PRKDC | P78527 | 7/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.57 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.57 |
| ▸ | ABL2 | P42684 | 3/20 | 0.49 |
| ▸ | RET | P07949 | 4/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19565379 | 0.92 | SRC (0.50) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL18599166 | 0.92 | SRC (0.50) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL24196837 | 0.92 | SRC (0.54) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL14693624 | 0.85 | SRC (0.64) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL24251864 | 0.85 | SRC (0.64) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL4821519 | 0.85 | SRC (0.64) | SRCEGFRABL1KDRPIK3CD | |
| Hydrochloric Acid SCHEMBL4826416 | 0.84 | SRC (0.63) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL24096479 | 0.84 | SRC (0.61) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL14646942 | 0.84 | KDR (0.45) | SRCEGFRABL1KDRPIK3CD | |
| SCHEMBL24197116 | 0.83 | KDR (0.46) | SRCEGFRABL1KDRPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |