SCHEMBL24251931 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	NR1H2	P55055	1/20	0.40

▸	UCHL1	P09936	1/20	0.39

▸	CHRM2	P08172	1/20	0.36

▸	CHRM1	P11229	1/20	0.36

▸	CHRM3	P20309	1/20	0.36

▸	ABCB1	P08183	1/20	0.35

▸	PDE4B	Q07343	1/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	POLB	P06746	1/20	0.34

▸	CYP3A4	P08684	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	HSD11B1	P28845	1/20	0.33

▸	AR	P10275	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21770659	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL29246157	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL29231967	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL1604238	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL19181227	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL13163960	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL1584687	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL7918399	0.88	NR1H2 (0.47)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL19179977	0.88	UCHL1 (0.36)	NR1H2UCHL1CHRM2CHRM1CHRM3
SCHEMBL23419844	0.88	NR1H2 (0.36)	NR1H2UCHL1CHRM2CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022033532-A1	FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF	上海和誉生物医药科技有限公司	2022-02-17	—	—	WO	disclosed