Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 2/20 | 0.35 |
| ▸ | ARG2 | P78540 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512016 | 0.87 | HSD17B10 (0.47) | DPP4DPP8ATMALDH1A1HSD17B10 | |
| SCHEMBL3512019 | 0.87 | HSD17B10 (0.47) | DPP4DPP8ATMALDH1A1HSD17B10 | |
| SCHEMBL792043 | 0.87 | HSD17B10 (0.47) | DPP4DPP8ATMALDH1A1HSD17B10 | |
| SCHEMBL1849871 | 0.85 | POLB (0.53) | DPP4DPP8ATMFKBP1AALDH1A1 | |
| SCHEMBL1849869 | 0.85 | POLB (0.53) | DPP4DPP8ATMFKBP1AALDH1A1 | |
| SCHEMBL1850667 | 0.85 | POLB (0.53) | DPP4DPP8ATMFKBP1AALDH1A1 | |
| SCHEMBL25960303 | 0.85 | ATM (0.35) | ATMFKBP1AALDH1A1HSD17B10POLB | |
| SCHEMBL25960304 | 0.83 | ALOX5AP (0.35) | ATMFKBP1AALDH1A1HSD17B10POLB | |
| SCHEMBL15196228 | 0.83 | DPP4 (0.36) | DPP4DPP8ATMFKBP1AALDH1A1 | |
| SCHEMBL15256201 | 0.83 | DPP4 (0.36) | DPP4DPP8ATMFKBP1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169922-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |