Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 11/20 | 0.62 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.36 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.36 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22132915 | 0.86 | ACVRL1 (0.58) | ACVRL1TYRO3PIK3CDMTORRICTOR | |
| SCHEMBL27315078 | 0.82 | ACVRL1 (0.47) | ACVRL1PIK3CD | |
| SCHEMBL19377690 | 0.78 | ACVRL1 (0.61) | ACVRL1TYRO3PIK3CDMTORRICTOR | |
| SCHEMBL14488443 | 0.78 | ACVRL1 (1.00) | ACVRL1 | |
| Hydrochloric Acid SCHEMBL29720772 | 0.77 | ACVRL1 (0.60) | ACVRL1TYRO3PIK3CDMTORRICTOR | |
| Hydrochloric Acid SCHEMBL19377754 | 0.77 | ACVRL1 (0.60) | ACVRL1TYRO3PIK3CDMTORRICTOR | |
| SCHEMBL23337052 | 0.77 | ACVRL1 (0.48) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL22132770 | 0.76 | ACVRL1 (0.41) | ACVRL1TYRO3PIK3CD | |
| SCHEMBL16011145 | 0.75 | ACVRL1 (1.00) | ACVRL1 | |
| SCHEMBL22004981 | 0.75 | PDE2A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022033532-A1 | FGFR AND MUTATION INHIBITOR THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海和誉生物医药科技有限公司 | 2022-02-17 | — | — | WO | disclosed |