Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415243 | 0.97 | DPP7 (0.47) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL11350779 | 0.94 | — | — | |
| SCHEMBL11069421 | 0.88 | — | — | |
| SCHEMBL14159625 | 0.76 | FDPS (0.36) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL11173567 | 0.74 | DPP7 (0.45) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL14159627 | 0.74 | FDPS (0.39) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL26986914 | 0.72 | DPP7 (0.48) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL3969170 | 0.72 | DPP7 (0.48) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL11687527 | 0.72 | DPP7 (0.48) | DPP7LMNAGAAFDPSALDH1A1 | |
| SCHEMBL3559523 | 0.72 | DPP7 (0.48) | DPP7LMNAGAAFDPSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022034203-A1 | PROCESS FOR THE PREPARATION OF PYRIDAZINONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-17 | — | — | WO | disclosed |