Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467679 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| SCHEMBL24252984 | 0.88 | KDM4C (0.43) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| SCHEMBL30451317 | 0.87 | CYP1A2 (0.46) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| SCHEMBL24252808 | 0.87 | CYP1A2 (0.46) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| Formic Acid SCHEMBL25237585 | 0.85 | KDM4C (0.41) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| SCHEMBL24252403 | 0.85 | CNR1 (0.43) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| SCHEMBL30467579 | 0.83 | CYP1A2 (0.41) | SMN1; SMN2CNR1CNR2ALDH1A1CYP1A2 | |
| SCHEMBL24252980 | 0.83 | CYP1A2 (0.41) | SMN1; SMN2CNR1CNR2ALDH1A1CYP1A2 | |
| SCHEMBL24252832 | 0.83 | CNR1 (0.42) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 | |
| SCHEMBL24252463 | 0.83 | KDM4C (0.45) | SMN1; SMN2CNR1CNR2KDM4CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | SMN1; SMN2 782/4885CNR1 2075/4885CNR2 1499/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | SMN1; SMN2 782/4885CNR1 2075/4885CNR2 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.